已发表论文

继发于局部布诺洛尔盐酸盐水溶液的缓慢性心律失常

 

Authors Lin LJ, Wang YC, Chen Y, Liu ML

Published Date October 2014 Volume 2014:9 Pages 1741—1745

DOI http://dx.doi.org/10.2147/CIA.S69420

Received 14 June 2014, Accepted 28 July 2014, Published 13 October 2014

Approved for publication by Professor Zhi-Ying Wu

Abstract: An 88-year-old man was admitted with fatigue, dizziness, and heart palpitations. Both the electrocardiogram and Holter confirmed the existence of sinus bradycardia and sinus arrest. One hour prior to the onset of symptoms, he received levobunolol hydrochloride solution topically. The levobunolol hydrochloride solution was discontinued and the bradycardia resolved. He was diagnosed as having intermittent sinus bradycardia and sinus arrest, induced by topical ß-blocker therapy. Levobunolol hydrochloride solution is an effective therapy for ocular hypertension, probably by reducing aqueous fluid production. However, it can induce cardiac side effects such as bradyarrhythmia and should be used with caution in elderly patients or patients with cardiac disease.
Keywords: bradycardia, topical ß-blocker, the elderly, glaucoma