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已发表论文
利多卡因季铵盐衍生物：过去、现在和未来
Authors Wang Q, Zhang Y, Liu J, Zhang W
Received 9 November 2020
Accepted for publication 25 December 2020
Published 14 January 2021 Volume 2021:15 Pages 195—207
DOI https://doi.org/10.2147/DDDT.S291229
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Georgios D. Panos
摘要：与全身镇痛药相比，局麻药具有镇痛完全、副作用少的优势。然而，由于其作用时间短，临床使用受到限制。因此，起效快、作用时间长、选择性伤害性阻滞、局部和全身毒性低的局麻药是非常需要的。在过去的电生理研究中，利多卡因季铵盐衍生物表现出这种可能性。在这里，我们综述了利多卡因季铵盐衍生物的电生理特性和药效学特性，以阐明潜在的问题。
关键词：利多卡因，局麻药，衍生物，QX-314