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治疗 COVID-19 时要警惕激素性股骨头缺血性坏死——来自 SARS 的经验与教训
Authors Zhang S, Wang C, Shi L, Xue Q
Received 22 December 2020
Accepted for publication 19 February 2021
Published 4 March 2021 Volume 2021:15 Pages 983—995
DOI https://doi.org/10.2147/DDDT.S298691
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Tin Wui Wong
摘要：2019 年爆发的冠状病毒病（COVID-19）已成为全球性疫情。COVID-19 感染与严重急性呼吸综合征（SARS）感染的病因及病理结果非常相似。糖皮质激素曾被广泛应用于 SARS 患者的治疗，然而，长期使用糖皮质激素（尤其是高剂量）与潜在的严重不良事件有关，特别是糖皮质激素诱导的股骨头缺血性坏死（SANFH）。在当今全球 COVID-19 疫情大爆发的情况下，是否该使用糖皮质激素治疗，治疗的剂量和持续时间，如何预防、早期发现和及时干预 SANFH 都是急需解决的重要问题。本文通过总结 SARS 治疗期间应用糖皮质激素的经验和教训，旨在为 COVID-19 流行国家和地区的卫生保健人员提供参考。
Keywords: COVID-19, steroid, necrosis of the femoral head, SARS